EC Number   |
Natural Substrates |
|---|
    2.3.1.230 | malonyl-CoA + 2-aminobenzoyl-CoA |
2-aminobenzoyl-CoA i.e. anthraniloyl-CoA |
| 2.3.1.230 | malonyl-CoA + 2-aminobenzoyl-CoA |
2-aminobenzoyl-CoA i.e. anthraniloyl-CoA. PqsD is a key enzyme in the biosynthesis of the signal molecules 2-heptyl-4-hydroxyquinoline and 4-hydroxy-2(1H)-quinolone, that are involved in regulation of virulence factor production and biofilm formation |
| 2.3.1.230 | malonyl-CoA + 2-aminobenzoyl-CoA |
2-aminobenzoyl-CoA i.e. anthraniloyl-CoA. The enzyme is involved in the biosynthesis of the Pseudomonas Quinolone Signal |
| 2.3.1.230 | malonyl-CoA + 2-aminobenzoyl-CoA |
the enzyme is involved in the biosynthesis of 2,4-dihydroxyquinoline. Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen that is a highly interactive organism secreting a variety of chemical signals. One intercellular signaling system unique to Pseudomonas and Burkholderia species is the production of hydrophobic quinolines. These quinoline derivatives are 4-hydroxy-2-heptylquinoline, 3,4-dihydroxy-2-heptylquinoline, and 2,4-dihydroxyquinoline |
| 2.3.1.230 | malonyl-CoA + 2-aminobenzoyl-CoA |
the enzyme is involved in the biosynthesis of the signal molecules 2-heptyl-3-hydroxy-4(1H)-quinolone and 4-hydroxy-2(1H)-quinolone. These compounds are part of the quorum-sensing systems that is based on the production and release of small signaling molecules, called autoinducers, that increase in concentration as a function of cell density and activate corresponding transcriptional regulators after a threshold concentration has been reached |
| 2.3.1.230 | octanoyl-CoA + (2-aminobenzoyl)acetate |
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