EC Number |
Natural Substrates |
---|
2.3.1.21 | acyl-CoA + L-carnitine |
- |
2.3.1.21 | acyl-CoA + L-carnitine |
CPT I activity is involved in cardiac mitochondrial beta-oxidation flux control |
2.3.1.21 | acyl-CoA + L-carnitine |
enzyme is involved in apoptosis induction |
2.3.1.21 | acyl-CoA + L-carnitine |
CPT I is the rate-limiting enzyme in beta-oxidation of long-chain fatty acids |
2.3.1.21 | acyl-CoA + L-carnitine |
enzyme has a key function in regulation of fatty acid beta-oxidation |
2.3.1.21 | acyl-CoA + L-carnitine |
CPT I, involved in regulation of fatty acid oxidation |
2.3.1.21 | more |
participates in fatty acyl group transport into mitochondria |
2.3.1.21 | more |
gamma-linolenic acid diet leads to several physiological effects during cancer therapy, e.g. reduction of mitochondrial metabolic activity, modification of mitochondrial outer membrane composition, increase in lipid peroxidation, cytoplasmic accumulation of acyl-CoA, reduction of CPT I activity, and malonyl-CoA sensitivity |
2.3.1.21 | more |
responsible for transferase activity on the outer side of the inner mitochondrial membrane |
2.3.1.21 | more |
CPT1-A defificiency presents as recurrent attacks of fasting hypoketotic hypoglycemia |