EC Number   |
Natural Substrates |
|---|
   2.3.1.161 | (4E,6E)-2-methyl-3-oxoocta-4,6-dienoyl-S-ACP + NADPH + H+ |
reaction of ketoreductase subunit, natural substrate. ACP = acyl-carrier protein |
| 2.3.1.161 | (4E,6E)-3-oxoocta-4,6-dienoyl-S-ACP + S-adenosyl-L-methionine |
reaction of methyltransferase subunit, natural substrate. ACP = acyl-carrier protein |
| 2.3.1.161 | 2-methyl-3-oxohexanoyl-N-acetylcysteamine + NADPH + H+ |
reaction of ketoreductase subunit, natural substrate |
| 2.3.1.161 | 3-oxohexanoyl-N-acetylcysteamine + NADPH + H+ |
reaction of ketoreductase subunit, natural substrate |
| 2.3.1.161 | acetyl-CoA + 8 malonyl-CoA + 11 NADPH + S-adenosyl-L-methionine + 11 H+ |
reaction mechanism |
| 2.3.1.161 | acetyl-CoA + 8 malonyl-CoA + 11 NADPH + S-adenosyl-L-methionine + 11 H+ |
reaction mechanism, interaction with LovC |
| 2.3.1.161 | acetyl-CoA + 8 malonyl-CoA + 11 NADPH + S-adenosyl-L-methionine + 11 H+ |
reaction mechanism, enzyme interacts with LovC to catalyze 35 separate reactions in the biosynthesis of dihydrononacolin |
| 2.3.1.161 | acetyl-CoA + malonyl-CoA + NADPH + H+ + S-adenosyl-L-methionine |
- |
| 2.3.1.161 | acetyl-CoA + malonyl-CoA + NADPH + H+ + S-adenosyl-L-methionine |
in the presence of the accessory protein LovC |
| 2.3.1.161 | acetyl-CoA + malonyl-CoA + NADPH + H+ + S-adenosyl-L-methionine |
in the absence of the accessory protein LovC, LovB forms conjugated pyrones as truncated polyketide synthase products |
