EC Number |
Natural Substrates |
---|
2.3.1.108 | acetyl-CoA + alpha-tubulin L-lysine |
- |
2.3.1.108 | acetyl-CoA + alpha-tubulin L-lysine |
post-translational modification of alpha-tubulin |
2.3.1.108 | acetyl-CoA + cortactin |
ATAT1 acetylates, binds and colocalizes with cortactin at the adherent surface of MDA-MB-231 cells |
2.3.1.108 | acetyl-CoA + [alpha-tubulin]-L-lysine |
- |
2.3.1.108 | acetyl-CoA + [alpha-tubulin]-L-lysine |
acetylation of alpha-tubulin mostly occurs on lysine residue 40, which is localized in the microtubule lumen |
2.3.1.108 | acetyl-CoA + [alpha-tubulin]-L-lysine |
acetylation of the epsilon-amino group of Lys40 |
2.3.1.108 | acetyl-CoA + [alpha-tubulin]-L-lysine |
acetylation of the epsilon-amino group of Lys40, in Tetrahymena, alpha-tubulin is the major if not the only substrate of MEC-17-dependent K acetylation |
2.3.1.108 | acetyl-CoA + [alpha-tubulin]-L-lysine |
K40 of alpha-tubulin is the sole site of acetylation by alphaTAT1, alphaTAT1 specifically acetylates K40 of alpha-tubulin and prefers microtubules over free tubulin, overview |
2.3.1.108 | acetyl-CoA + [alpha-tubulin]-L-lysine40 |
- |
2.3.1.108 | more |
alphaTAT/MEC-17 is a lysine acetyltransferase for tubulin and not histones |