EC Number |
Natural Substrates |
---|
2.3.1.1 | acetyl-CoA + L-glutamate |
- |
2.3.1.1 | acetyl-CoA + L-glutamate |
enzyme activates carbamoyl-phosphate synthase ammonia in small intestine mucosa, to allow citrulline synthesis in the tissue |
2.3.1.1 | acetyl-CoA + L-glutamate |
enzyme catalyzes the first step in arginine biosynthesis |
2.3.1.1 | acetyl-CoA + L-glutamate |
first enzyme in urea cycle |
2.3.1.1 | acetyl-CoA + L-glutamate |
indispensible enzyme of arginine biosynthesis |
2.3.1.1 | acetyl-CoA + L-glutamate |
enzyme catalyzes the first step in the biosynthesis of arginine |
2.3.1.1 | acetyl-CoA + L-glutamate |
initial step of the L-arginine biosynthesis, pathway overview |
2.3.1.1 | acetyl-CoA + L-glutamate |
the product N-acetyl-L-glutamate serves as an allosteric activator of carbamoylphosphate synthetase 1, the first enzyme of the urea cycle. Autosomal recessive inherited NAGS deficiency leads to severe neonatal or late-onset hyperammonemia |
2.3.1.1 | acetyl-CoA + L-glutamate |
NAGS is the first enzyme of arginine biosynthesis, microbial arginine biosynthesis pathway, overview. Arginine is an allosteric inhibitor of microbial NAGS, arginine is also an inhibitor of plant NAGS, a partial inhibitor of fish NAGS, but an allosteric activator of mammalian NAGS |
2.3.1.1 | acetyl-CoA + L-glutamate |
ability of protein Cg3035 to acetylate L-glutamate in vitro and in vivo |