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Results 1 - 10 of 107 > >>
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EC Number Natural Substrates Commentary (Nat. Sub.)
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.202more identification of single-nucleotide resolution of cytosine 5-methylation sites in non-coding ribosomal RNAs and transfer RNAs of all three subcellular transcriptomes across six diverse species, overview. The enzyme does not methylate cytosines at structural positions C47, C48, C49 and C72. Identification of modified cytosines in Arabidopsis thaliana nuclear transcribed tRNAs which are dependent on RMTases TRDMT1 and TRM4B. No cytosine 5-methylation sites are detected in Arabidopsis chloroplast or mitochondrial tRNAs, which is in contrast to animal mitochondrial tRNAs
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.202more identification of single-nucleotide resolution of m5C sites in non-coding ribosomal RNAs and transfer RNAs of all three subcellular transcriptomes across six diverse species, overview
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.202more NSUN2 candidate ncRNA targets identified include RNAs with central functions in the processing, folding and modification of other ncRNAs (RPPH1, Y RNA, SCARNA2), RNAs important for protein synthesis and trafficking (5S rRNA and 7SL RNA) and RNAs involved in multidrug resistance and other processes (Vault RNAs). Notably, all of the NSUN2 targets revealed by 5-azacytidine-mediated RNA immunoprecipitation are either transcribed by RNA Pol III in the nucleolus (SCARNA2 excepted), or function in the nucleolus (SCARNA2), where NSUN2 resides
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.202more the enzyme Trm4 fabricate 5-methylcytosine (m5C) in RNA molecules utilizing a dual-cysteine catalytic mechanism
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.202more the iCLIP method identifies tRNA AspGTC, ValAAC, GlyGCC, and LeuCAA as methylation substrates with methylation within the variable arm at cytosines 48, 49, and 50, no additional NSun2 target sites outside the variable arm. vtRNAs are methylation substrates for NSun2, vtRNAs are ncRNAs found as part of the vault ribonucleoprotein complex
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.202S-adenosyl-L-methionine + cytosine in tRNA precursor -
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.202S-adenosyl-L-methionine + cytosine15 in vtRNA1.3 -
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.202S-adenosyl-L-methionine + cytosine27 in vtRNA1.2 -
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.202S-adenosyl-L-methionine + cytosine27 in vtRNA1.3 -
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.202S-adenosyl-L-methionine + cytosine34 in tRNA -
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