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EC Number
Natural Substrates
Commentary (Nat. Sub.)
2.1.1.183
4 S-adenosyl-L-methionine + adenine1779/adenine1780 in 18S rRNA
Dim1p is required for pre-ribosomal RNA processing
2.1.1.183
4 S-adenosyl-L-methionine + adenine1779/adenine1780 in 18S rRNA
isolation of mutations that uncouple the enzymatic function of Dim1p in methylation from its involvement in prerRNA processing
2.1.1.183
4 S-adenosyl-L-methionine + adenine1779/adenine1780 in 18S rRNA
neither the bacterial nor the archaeal ortholog could complement for the eukaryotic Dim1. This might be related to the secondary, non-methyltransferase function that Dim1 is known to play in eukaryotic ribosomal maturation
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