EC Number   |
Natural Substrates |
|---|
   2.1.1.142 | cycloartenol + S-adenosyl-L-methionine |
- |
| 2.1.1.142 | cycloartenol + S-adenosyl-L-methionine |
cycloartenol is 4,4,14alpha-trimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol |
| 2.1.1.142 | cycloartenol + S-adenosyl-L-methionine |
rate-limiting initial step in the conversion of phytosterol |
| 2.1.1.142 | cycloartenol + S-adenosyl-L-methionine |
SMT2 has a position-specific substrate specificity for DELTA24(25)-sterols and contains a single active center to catalyze the consecutive C1-transfer activities by substrate reaction channels similar to the fungal SMT1 |
| 2.1.1.142 | more |
GC-MS analysis shows that the fungus synthesizes 12 compounds of which lanosterol, ergosterol and brassicasterol make up approximately 80% of the sterol mixture |
| 2.1.1.142 | S-adenosyl-L-methionine + 5alpha-cholesta-8,24-dien-3beta-ol |
3-hydroxy-3-methylglutaryl CoA reductase and C24-sterol methyltransferase type 1 work in concert to control carbon flux into end-product sterols. Sterol composition can be controlled by the temporal activity of the promoters driving transgene expression |
| 2.1.1.142 | S-adenosyl-L-methionine + cycloartenol |
- |
| 2.1.1.142 | S-adenosyl-L-methionine + lanosterol |
PbSMT synthesizes a single product, eburicol 24(28)-methylene-24,25-dihydro-lanosterol, from lanosterol |
| 2.1.1.142 | zymosterol + S-adenosyl-L-methionine |
- |
