EC Number   |
Natural Substrates |
|---|
    1.7.3.3 | more |
enzyme catalyzes the oxidation of uric acid to a more soluble and easily excreted compound, allantoin |
| 1.7.3.3 | more |
purine degradation, urate oxidase catalyzes the oxidation of uric acid with poor solubility to produce 5-hydroxyisourate and allantoin |
| 1.7.3.3 | more |
rasburicase acts at the end of the purine catabolic pathway, and unlike allopurinol, it does not induce accumulation of xanthine or hypoxanthine |
| 1.7.3.3 | urate + O2 + H2O |
- |
| 1.7.3.3 | urate + O2 + H2O |
ureide pathway |
| 1.7.3.3 | urate + O2 + H2O |
enzyme production is induced by addition of uric acid to the culture medium |
| 1.7.3.3 | urate + O2 + H2O |
first step in uric acid degradation |
| 1.7.3.3 | urate + O2 + H2O |
purine metabolism |
| 1.7.3.3 | urate + O2 + H2O |
urate oxidase catalyzes the hydroxylation of uric acid into the metastable product 5-hydroxyisourate in the presence of molecular oxygen as part of the purine degradation pathway. 5-Hydroxyisourate decays slowly to allantoin, a process independent of oxygen and associated with the release of CO |
| 1.7.3.3 | uric acid + O2 + H2O |
purine degradation |
