EC Number   |
Natural Substrates |
|---|
    1.5.1.3 | 10-formyl-dihydrofolate + NADPH + H+ |
the enzyme is involved in the folate recycling pathway |
| 1.5.1.3 | 7,8-dihydrobiopterin + NADPH + H+ |
- |
| 1.5.1.3 | 7,8-dihydrofolate + NADH + H+ |
- |
| 1.5.1.3 | 7,8-dihydrofolate + NADPH |
- |
| 1.5.1.3 | 7,8-dihydrofolate + NADPH |
maintainance of adequate levels of fully reduced folate in metabolism of proliferating cells |
| 1.5.1.3 | 7,8-dihydrofolate + NADPH |
key enzyme in biosynthesis of purines, pyrimidines and several amino acids |
| 1.5.1.3 | 7,8-dihydrofolate + NADPH |
key role in thymidylate biosynthesis |
| 1.5.1.3 | 7,8-dihydrofolate + NADPH |
DHFR activity is not essential for virus replication |
| 1.5.1.3 | 7,8-dihydrofolate + NADPH |
directly correlated with thymidylate synthesis |
| 1.5.1.3 | 7,8-dihydrofolate + NADPH + H+ |
- |
