EC Number   |
Natural Substrates |
|---|
    1.5.1.20 | (6R)-5,10-methylenetetrahydrofolate + NAD(P)H + H+ |
- |
| 1.5.1.20 | 5,10-methylenetetrahydrofolate + FADH2 |
- |
| 1.5.1.20 | 5,10-methylenetetrahydrofolate + FADH2 |
biosynthesis of 5-methyltetrahydrofolate, a donor of methyl groups of methionine |
| 1.5.1.20 | 5,10-methylenetetrahydrofolate + FADH2 |
first step of conversion of 5,10-methylenetetrahydrofolate to methionine |
| 1.5.1.20 | 5,10-methylenetetrahydrofolate + FADH2 |
enzyme in pathway of synthesis of acetate from CO2 via formate and a series of reactions involving tetrahydrofolate and a corrinoid, FADH2 and reduced ferredoxin may serve as natural reductants for 5,10-methylenetetrahydrofolate |
| 1.5.1.20 | 5,10-methylenetetrahydrofolate + ferredoxin |
- |
| 1.5.1.20 | 5,10-methylenetetrahydrofolate + NAD(P)H + H+ |
- |
| 1.5.1.20 | 5,10-methylenetetrahydrofolate + NADH |
- |
| 1.5.1.20 | 5,10-methylenetetrahydrofolate + NADH |
folate-mediated one-carbon metabolism |
| 1.5.1.20 | 5,10-methylenetetrahydrofolate + NADH |
physiological direction is the 5-methyltetrahydrofolate formation by transfer of reducing equivalents from NADH to the enzyme-bound FAD and from reduced FAD to methylenetetrahydrofolate |
