EC Number   |
Natural Substrates |
|---|
    1.2.1.8 | 3-aminopropionaldehyde + NAD+ + H2O |
- |
| 1.2.1.8 | 4-aminobutyraldehyde + NAD+ + H2O |
- |
| 1.2.1.8 | betaine aldehyde + NAD(P)+ + H2O |
- |
| 1.2.1.8 | betaine aldehyde + NAD+ + H2O |
- |
| 1.2.1.8 | betaine aldehyde + NAD+ + H2O |
the enzyme catalyzes the second step in the synthesis of the osmoprotectant glycine betaine |
| 1.2.1.8 | betaine aldehyde + NAD+ + H2O |
the osmoprotective compound glycine betaine is produced from choline by two enzymes. Choline dehydrogenase oxidizes choline to betaine aldehyde and then further to glycine betaine, while betaine aldehyde dehydrogenase facilitates the conversion of betaine aldehyde to glycine betaine |
| 1.2.1.8 | betaine aldehyde + NAD+ + H2O |
belongs to the NAD-dependent dehydrogenase family, characterized by the typical aldehyde substrate binding domain |
| 1.2.1.8 | betaine aldehyde + NAD+ + H2O |
enzyme is induced several-fold by salinization |
| 1.2.1.8 | betaine aldehyde + NAD+ + H2O |
the enzyme has an important function in the metabolism of choline to betaine, a major osmolyte. Betaine is also important in mammalian organisms as a major methyl group donor and nitrogen source |
| 1.2.1.8 | betaine aldehyde + NAD+ + H2O |
the enzyme is involved in the metabolism of choline, induced during growth on choline |
