EC Number |
Natural Substrates |
---|
1.2.1.10 | acetaldehyde + CoA + NAD+ |
- |
1.2.1.10 | acetaldehyde + CoA + NAD+ |
ethanol production in aerobic glucose dissimilation |
1.2.1.10 | acetaldehyde + CoA + NAD+ |
during glucose fermentation |
1.2.1.10 | acetaldehyde + CoA + NAD+ |
during ethanol fermentation |
1.2.1.10 | acetaldehyde + CoA + NAD+ |
involved in degradation of toxic aromatic compounds via the intermediate catechol |
1.2.1.10 | acetyl-CoA + NADH + H+ |
- |
1.2.1.10 | acetyl-CoA + NADH + H+ |
best substrate |
1.2.1.10 | butanoyl-CoA + NADH + H+ |
- |
1.2.1.10 | formaldehyde + CoA + NAD+ |
- |
1.2.1.10 | more |
DmpFG is a bifunctional enzyme comprised of an aldolase subunit, DmpG, and a dehydrogenase subunit, DmpF. The aldehyde intermediate produced by the aldolase is channeled directly through a buried molecular channel in the protein structure from the aldolase to the dehydrogenase active site. Binding and channeling of alternative substrates in the enzyme DmpFG, molecular dynamics, overview |