EC Number |
Natural Substrates |
---|
1.14.99.22 | ecdysone + AH2 + O2 |
- |
1.14.99.22 | ecdysone + AH2 + O2 |
the enzyme is responsible for the conversion of the molting hormone ecdysone to its more physiologically active metabolite, 20-hydroxyecdysone |
1.14.99.22 | ecdysone + NADPH + H+ + O2 |
- |
1.14.99.22 | ecdysone + NADPH + O2 |
- |
1.14.99.22 | ecdysone + NADPH + O2 |
serves as precursor of ecdysterone, the active moulting hormone in larval insects |
1.14.99.22 | ecdysone + NADPH + O2 |
alpha-ecdysone, a secretory product of prothoracic glands |
1.14.99.22 | ecdysone + NADPH + O2 |
last step in biosynthesis of insect molting hormone |
1.14.99.22 | ecdysone + NADPH + O2 |
midgut microsomes show higher specific activity with 2fold higher Vmax, while total activity is 8-10fold higher in mitochondria |
1.14.99.22 | ecdysone + reduced acceptor + O2 |
- |
1.14.99.22 | more |
E20-M preferentially uses NADPH in catalyzing ecdysone conversion to the physiologically active molting hormone, 20-hydroxyecdysone |