EC Number   |
Natural Substrates |
|---|
   1.14.17.3 | calcitonin + ascorbate + O2 |
- |
| 1.14.17.3 | glutathione + ascorbate + O2 |
- |
| 1.14.17.3 | insulin + ascorbate + O2 |
- |
| 1.14.17.3 | more |
cleavage of CN bond in N-acetylated glycines, R-CO-NH-CH2-COOH, e.g. found in neuropeptide prohormones, inhibition of the enzyme leads to a decrease in alpha-aminated peptide production and accumulation of glycine-extended precursors |
| 1.14.17.3 | more |
enzyme catalyzes the biosynthesis of peptide hormones through radical cleavage of the C-terminal glycine residues of the corresponding prohormones |
| 1.14.17.3 | more |
enzyme catalyzes the production of neurohormones and neurotransmitters |
| 1.14.17.3 | more |
enzyme is involved in peptide posttranslational activation |
| 1.14.17.3 | more |
enzyme is required for amidation of autocrine growth factors causing proliferation in tumor cells |
| 1.14.17.3 | more |
enzyme is required for amidation of the C-terminus of neuropeptides |
| 1.14.17.3 | more |
enzyme might be involved in secretory vesicle budding and fusion in the cardiac ANP-secretory pathway |
