EC Number   |
Natural Substrates |
|---|
   1.14.15.28 | cholest-4-en-3-one + 6 reduced [2Fe-2S] ferredoxin |
- |
| 1.14.15.28 | cholest-4-en-3-one + 6 reduced [2Fe-2S] ferredoxin + 3 O2 |
the enzyme can receive electrons from ferredoxin reductase in vitro, its natural electron donor is not known yet. The enzyme of the bacterial pathogen is involved degradation of the host cholesterol |
| 1.14.15.28 | cholest-4-en-3-one + 6 reduced [2Fe-2S] ferredoxin + 3 O2 |
dominant P450 enzyme responsible for initiating steroid side chain degradation in Mycobacterium tuberculosis. It is suggested that cholest-4-en-3-one rather than cholesterol is the most relevant in vivo substrate |
| 1.14.15.28 | cholest-4-en-3-one + 6 reduced [2Fe-2S] ferredoxin + 3 O2 |
the enzyme participates in cholesterol degradation |
