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Results 1 - 10 of 36

EC Number	Natural Substrates	Commentary (Nat. Sub.)
1.1.1.B40	11-dehydrocorticosterone + NADPH	isozyme 11beta-HSD1
1.1.1.B40	11beta,17,21-trihydroxy-pregn-4-ene-3,20-dione + NAD+	i.e. cortisol
1.1.1.B40	11beta,21-dihydroxypregn-4-en-3,20-dione + NAD+	isoform 11beta-HSD2
1.1.1.B40	11beta,21-dihydroxypregn-4-en-3,20-dione + NAD+	i.e. corticosterone
1.1.1.B40	11beta,21-dihydroxypregn-4-en-3,20-dione + NAD+	i.e. corticosterone, clear but not exclusive preference for NAD+, only oxidative activity
1.1.1.B40	11beta,21-dihydroxypregn-4-en-3,20-dione + NAD+	i.e. corticosterone, no enzyme activity in reverse reaction direction
1.1.1.B40	11beta,21-dihydroxypregn-4-en-3,20-dione + NAD+	i.e. corticosterone, significant higher rate of conversion for 11-beta-HSD2 than for 11-beta-HSD1
1.1.1.B40	11beta-hydroxytestosterone + NAD+	-
1.1.1.B40	17,21-dihydroxy-pregn-4-ene-3,11,20-trione + NADH	i.e. cortisone
1.1.1.B40	17,21-dihydroxy-pregn-4-ene-3,11,20-trione + NADH	important role in modulating mineralocorticoid and glucocorticoid receptor occupancy by glucocorticoids

Results 1 - 10 of 36

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Release 2023.1 (January 2023)