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Results 1 - 10 of 50

EC Number	Natural Substrates	Commentary (Nat. Sub.)
1.1.1.62	17beta-estradiol + NAD(P)+	-
1.1.1.62	17beta-estradiol + NAD+	-
1.1.1.62	17beta-estradiol + NADP+	-
1.1.1.62	4-androstene-3,17-dione + NADPH + H+	17beta-HSD3 and 5, formation of active androgens in testis and prostate
1.1.1.62	4-estrene-3,17-dione + NADPH	-
1.1.1.62	5alpha-androstane-3alpha,17beta-diol + NAD+	-
1.1.1.62	5alpha-dihydrotestosterone + NADP+	the enzyme could play a critical role in estrogen-sensitive cells, since it inactivates 5alpha-dihydrotestosterone that generally shows antagonistic effect in the cells
1.1.1.62	androstenedione + NAD(P)H + H+	-
1.1.1.62	estradiol-17beta + NAD(P)+	17beta-HSD2 and 5, key role in regulating steroid receptor occupancy in normal and tumor tissues
1.1.1.62	estradiol-17beta + NAD(P)+	17beta-HSD4 is involved in etsrogen inactivation and may protect against an excessive accumulation of E2 in human ovarian epithelial cells

Results 1 - 10 of 50

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Release 2023.1 (January 2023)