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EC Number
Natural Substrates
Commentary (Nat. Sub.)
1.1.1.406
D-arabitol + NAD+
-
1.1.1.406
D-ribulose + NADH
-
1.1.1.406
D-threitol + NAD+
best substrate tested
1.1.1.406
D-xylulose + NADH
-
1.1.1.406
galactitol + NAD+
-
1.1.1.406
L-erythrulose + NADH
-
1.1.1.406
L-glucitol + NAD+
-
1.1.1.406
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GatDH catalyzes the dehydrogenation of a variety of polyvalent aliphatic alcohols and polyols to the corresponding ketones and ketoses, respectively, and in the reverse reaction it reduces prochiral ketones with high stereoselectivity yielding the corresponding S-configured secondary alcohols
1.1.1.406
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GatDH from Rhodobacter sphaeroides is a multifunctional enzyme that catalyzes in the presence of oxidized beta-NAD+ the interconversion of various multivalent aliphatic alcohols to the corresponding ketone. GatDH oxidizes a variety of polyvalent aliphatic alcohols and polyols to the corresponding ketones and ketoses, respectively, and in the reverse reaction, it reduces ketones with high stereoselectivity yielding the corresponding S-configurated alcohols
1.1.1.406
xylitol + NAD+
-
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