EC Number   |
Natural Substrates |
|---|
    1.1.1.39 | (S)-malate + NAD(P)+ |
- |
| 1.1.1.39 | (S)-malate + NAD+ |
- |
| 1.1.1.39 | (S)-malate + NAD+ |
enzyme is involved in carbon fixation and metabolism, regulation of the pathways, overview |
| 1.1.1.39 | (S)-malate + NAD+ |
mitochondrial isozyme ME2 responds to elevated amino acids and serves to supply sufficient pyruvate for increased Krebs cycle flux when glucose is limiting |
| 1.1.1.39 | (S)-malate + NAD+ |
the enzyme plays a central role in the metabolite flux through the tricarboxylic acid cycle, overview |
| 1.1.1.39 | (S)-malate + NAD+ |
the enzyme plays a role in symbiotic N2 fixation, overview |
| 1.1.1.39 | (S)-malate + NAD+ |
the enzyme plays a special role in the decarboxylation of C4 acids to pyruvate and CO2, which are used in subsequent photosynthesis. pH, NAD+, and coenzyme A levels in the matrix act together to regulate (S)-malate oxidation |
| 1.1.1.39 | (S)-malate + NAD+ |
NAD-ME1, -ME2 and -MEH catalyse the reverse reaction of pyruvate reductive carboxylation with very low catalytic activity, supporting the notion that these isoforms act only in (S)-malate oxidation in plant mitochondria |
| 1.1.1.39 | (S)-malate + NAD+ |
the enzyme acts preferably in the direction of malate decarboxylation, the reverse reaction proceeds with much lower rate |
| 1.1.1.39 | (S)-malate + NADP+ |
- |
