EC Number   |
Natural Substrates |
|---|
    5.3.2.6 | (2Z,4E)-2-hydroxyhexa-2,4-dienedioate |
- |
| 5.3.2.6 | 2-hydroxy-2,4-pentadienoate |
- |
| 5.3.2.6 | 2-hydroxymuconate |
- |
| 5.3.2.6 | phenylenolpyruvate |
- |
| 5.3.2.6 | 2-oxo-4(E)-hexenedioate |
1,3-allylic isomerization |
| 5.3.2.6 | 2-hydroxy-2,4-hexadienedioate |
i.e. 2-hydroxymuconate |
| 5.3.2.6 | 2-oxo-4-hexenedioate |
isomerization of unconjugated 2-oxo acids such as 2-oxo-4-hexenedioate, to its conjugated isomer via dienol intermediate 2-hydroxy-2,4-hexadienedioate, i.e. 2-hydroxymuconate |
| 5.3.2.6 | 2-hydroxymuconate |
ketonization |
| 5.3.2.6 | 2-oxo-4-hexenedioate |
ketonization process via dienol intermediate 2-hydroxymuconate and with Pro1 as a general base, one-proton transfer mechanism |
| 5.3.2.6 | 2-hydroxymuconate |
the conjugated enol, 2-hydroxymuconate is an unusually stable dienol that is reportedly generated in the course of bacterial catabolism of catechol by the enzymes of the meta-fission pathway |
