EC Number |
Natural Substrates |
---|
3.5.1.2 | L-Gln + H2O |
- |
3.5.1.2 | L-glutamine + H2O |
- |
3.5.1.2 | L-glutamine + H2O |
biosynthesis of pyridoxal-5-phosphate |
3.5.1.2 | L-Gln + H2O |
constitutive enzyme |
3.5.1.2 | L-Gln + H2O |
contribution of the enzyme to elevated extracellular Glu at 24 h after onset of focal ischemia |
3.5.1.2 | L-Gln + H2O |
enzyme is involved in deamination of Gln to Glu, which is utilized for energy production via the TCA cycle. Glutaminase mRNA increases around the 3rd week of life |
3.5.1.2 | L-glutamine + H2O |
enzyme participates in an ATP-consuming cycle, plays a catabolic role in the degradation of glutamine to carbon skeletons, maintaining the optimal balance between glutamine and glutamate |
3.5.1.2 | L-Gln + H2O |
enzyme plays a key role in urea synthesis by regulating provision of glutamate for synthesis of N-acetylglutamate, the obligatory cofactor of carbamoylphosphate synthetase |
3.5.1.2 | L-glutamine + H2O |
glutamate is an important source for neurotransmitter |
3.5.1.2 | more |
glutaminase as a potential component of the pathogenic process of human immunodeficiency virus associated dementia |