EC Number   |
Natural Substrates |
|---|
   3.4.24.B6 | amelogenin + H2O |
- |
| 3.4.24.B6 | enamelin + H2O |
- |
| 3.4.24.B6 | proteins + H2O |
- |
| 3.4.24.B6 | ameloblastin + H2O |
N-terminal ameloblastin cleavage products of 13, 15, and 17 kDa accumulate in the sheath space throughout the enamel layer |
| 3.4.24.B6 | cartilage oligomeric matrix protein + H2O |
100 kDa protein substrate |
| 3.4.24.B6 | amelogenin + H2O |
amelogenin constitutes more than 90% of enamel extracellular matrix proteins in secretory-stage enamel |
| 3.4.24.B6 | amelogenin + H2O |
amelogenin with a proline 41 to threonine mutation is hydrolyzed at a lower rate by matrix metalloproteinase 20 (MMP20), resulting in an inherited tooth enamel defect, amelogenesis |
| 3.4.24.B6 | aggrecan + H2O |
cleavage site is Asn341-Phe342 |
| 3.4.24.B6 | more |
degradation of various components of the extracellular matrix during tooth development and pathological conditions |
| 3.4.24.B6 | amylogenin + H2O |
involved in tooth formation |
