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Results 1 - 5 of 5
EC Number
Natural Substrates
Commentary (Nat. Sub.)
the virus can regulate in vivo proteinase activity through self inactivation of PLP-1. The lack of p50 production in cells infected with the mouse hepatitis virus strain JHM may regulate PLP-1 activity differently from MHV-59
ORF 1a polyprotein + H2O
cleavage in cis and in trans. PLP-1 cleavage activity appears to be optimal when both enzyme and substrate are present as part of polyproteins, as they are in the virus replication cycle
ORF 1a polyprotein + H2O
the enzyme is involved in processing of ORF 1a polyprotein into mature replicase-related polypeptides
Results 1 - 5 of 5