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EC Number
Natural Substrates
Commentary (Nat. Sub.)
3.4.22.49
cohesin + H2O
-
3.4.22.49
kendrin + H2O
-
3.4.22.49
Rad 21 + H2O
-
3.4.22.49
Rad21 + H2O
-
3.4.22.49
Rec8 + H2O
-
3.4.22.49
Scc1 + H2O
-
3.4.22.49
Slk19 + H2O
-
3.4.22.49
Slk19 + H2O
a protein implicated in the mitotic exit via its role in the stabilization of spindle in budding yeast
3.4.22.49
more
auto-cleavage of separase coordinates multiple aspects of the G2/M programme in human cells, thus contributing to the timing and efficiency of chromosome segregation
3.4.22.49
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autocleavage of human separase is to be essential and results in conformational changes
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