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Results 1 - 10 of 44 > >>
EC Number
Natural Substrates
Commentary (Nat. Sub.)
Cdc14 + H2O
separase regulates INCENP-Aurora B anaphase spindle function through activation of Cdc14
cohesin + H2O
-
cohesin + H2O
separase is required for sister chromatid separation during mitosis
cohesin + H2O
separase, i.e. Esp1, is implicated in the removal of cohesin which links sister chromatids in the S-phase and is postulated to be a specific protease or a positive regulator of protease against cohesin
cohesin + H2O
separase triggers anaphase by cohesin cleavage, and triggers the release and activation of the phosphatase Cdc14 independently of its protease activity
cohesin + H2O
separase-mediated cleavage of cohesin at interphase is required for DNA repair. It is proposed that the securin-separase complex might aid DNA repair by removing local cohesin in interphase cells
cohesin + H2O
cohesin cleavage by human separase requires DNA in a sequence-nonspecific manner
cohesin + H2O
separase selectively cleaves only the chromosome-associated cohesin with the cofactor chromosomal DNA
cohesin + H2O
separase selectively cleaves only the chromosome-associated cohesin with the cofactor chromosomal DNA, chromosome-associated cohesin is cleaved preferentially by separase, mechanism
cohesin + H2O
chromatin-bound cohesion is the preferential substrate
Results 1 - 10 of 44 > >>