EC Number |
Natural Substrates |
---|
3.1.2.22 | palmitoyl-[protein] + H2O |
- |
3.1.2.22 | more |
altough the ppt-1 gene is not essential for the animals survival, its mutation results in a mild developmental and reproductive phenotype, affects the number and size of mitochondria and results in an abnormality in mitochondrial morphology |
3.1.2.22 | more |
defect in the palmitoyl-(protein) hydrolase gene causes a neurodegenerative disorder. Depalmitoylation of the still uncharacterized substrate(s) of the enzyme is critical for postnatal development or maintainance of cortical neurons |
3.1.2.22 | more |
depalmitoylation reaction, palmitoylation is the post-translational addition of a palmitate moiety to a cysteine residue through a covalent thioester bond |
3.1.2.22 | more |
enzyme deficiency causes infantile neuronal ceroid lipofuscinosis, the enzyme plays an important role in the development of the CNS |
3.1.2.22 | more |
enzyme deficiency causes progressive neurological and granular osmiophilic deposits, GROD, and infantile neuronal ceroid lipofuscinosis |
3.1.2.22 | more |
enzyme deficiency causes progressive neurological disorder infantile neuronal ceroid lipofuscinosis, INCL |
3.1.2.22 | more |
enzyme deficiency causes progressive neurological disorder infantile neuronal ceroid lipofuscinosis, INCL, a lysosomal storage disorder |
3.1.2.22 | more |
enzyme deficiency causes progressive neurological disorder infantile neuronal ceroid lipofuscinosis, INCL, molecular basis |
3.1.2.22 | more |
enzyme deficiency causes the infantile form of neuronal ceroid lipofuscinosis INCL, a progressive encephalopathyof children |