EC Number   |
Natural Substrates  |
|---|
   1.14.19.3 | alpha-linolenic acid + AH2 + O2 |
the enzyme is responsible for the first and rate-limiting step in biosynthesis of highly unsaturated fatty acids |
| 1.14.19.3 | alpha-linolenoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ |
- |
| 1.14.19.3 | alpha-linolenoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ |
preferred substrate |
| 1.14.19.3 | alpha-linolenoyl-CoA + ferrocytochrome b5 + O2 + H+ |
- |
| 1.14.19.3 | alpha-linoleoyl-CoA + AH2 + O2 |
- |
| 1.14.19.3 | linoleic acid + AH2 + O2 |
- |
| 1.14.19.3 | linoleic acid + AH2 + O2 |
key enzyme localized in the endoplasmic reticulum |
| 1.14.19.3 | linoleic acid + AH2 + O2 |
important for the generation of unsaturated fatty acids, DELTA6-desaturase required for the conversion of dietary linoleic acid to arachidonic acid |
| 1.14.19.3 | linoleic acid + AH2 + O2 |
DELTA6-desaturase reaction is the rate-limiting step in the conversion of linoleic acid and alpha linoleic acids to the longer, more highly unsaturated members of the n-6 and n-3 polyunsaturated fatty acids, metabolic pathway in mammalian cells |
| 1.14.19.3 | linoleic acid + AH2 + O2 |
the enzyme is responsible for the first and rate-limiting step in biosynthesis of highly unsaturated fatty acids |
