EC Number |
Natural Substrates |
---|
1.13.11.34 | (5S,6E,8Z,11Z,14Z)-5-hydroperoxyicosa-6,8,11,14-tetraenoate |
epoxidation |
1.13.11.34 | (5Z,8Z,10E,12S,14Z)-12-hydroxyicosa-5,8,10,14-tetraenoic acid + O2 |
- |
1.13.11.34 | (6E,8Z,11Z,14Z)-(5S)-5-hydroperoxyeicosa-6,8,11,14-tetraenoate |
- |
1.13.11.34 | (6E,8Z,11Z,14Z)-(5S)-5-hydroperoxyeicosa-6,8,11,14-tetraenoate |
efficient LTA4 formation of 5LO requires both phosphatidyl choline and coactosin-like protein |
1.13.11.34 | 5-hydroperoxyeicosatetraenoic acid |
- |
1.13.11.34 | arachidonate + O2 |
- |
1.13.11.34 | arachidonate + O2 |
hydroperoxidation |
1.13.11.34 | arachidonate + O2 |
overall reaction |
1.13.11.34 | arachidonic acid + O2 |
- |
1.13.11.34 | arachidonic acid + O2 |
first committed step in the synthesis of leukotrienes |