Refine search

Search Natural Substrates/ Products (Substrates)

show results
Don't show organism specific information (fast!)
Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)
(Not possible to combine with the first option)
Refine your search
Search for synonyms (with exact matching search term)

Search term:

Results 1 - 8 of 8
EC Number
Natural Substrates
Commentary (Nat. Sub.)
4-hydroxyphenylpyruvate + O2
4-hydroxyphenylpyruvate + O2
enzyme participates in catabolism of tyrosine
4-hydroxyphenylpyruvate + O2
key enzyme involved in tyrosine catabolism, congenital 4-hydroxyphenylpyruvate dioxygenase deficiency is a rare, relatively benign condition known as hereditary type III tyrosinemia
4-hydroxyphenylpyruvate + O2
enzyme is involved in production of homogentisate, the aromatic precursor of all phenylquinones
4-hydroxyphenylpyruvate + O2
hppD is transcriptionally activated by HpdA and repressed by HpdR
4-hydroxyphenylpyruvate + O2
the conversion of 4-hydroxyphenyl-pyruvate to homogentisate involves oxidative decarboxylation, side-chain migration and aromatic hydroxylation in a single catalytic cycle. The 4-HPPD reaction is unusual in that the 2-oxoacid and prime substrate moieties are contained within the same molecule
4-hydroxyphenylpyruvate + O2
second step of oxidative tyrosine catabolism
HpdR positively regulates hpdA expression through direct binding to the HpdA promoter within a region containing two conserved direct repeat sequences. HpdR-dependent hpdA transcription occurs in the presence of 4-hydroxyphenylpyruvate, tyrosine, and phenylalanine, as well as during starvation
Results 1 - 8 of 8