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EC Number
Natural Substrates
Commentary (Nat. Sub.)
5.3.1.8
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enzyme is involved in biosynthesis of mannan components of the cell walls
5.3.1.8
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adaptive enzyme
5.3.1.8
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critical role in the supply of the D-mannose derivatives required for many glycosylation reactions
5.3.1.8
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reversible isomerization of mannose 6-phosphate and fructose 6-phosphate is the initial commited step in the synthesis of the mannosylated glycoproteins, which are essential in biosynthesis of functional fungal cell wall. Absence of mannose-6-phosphate isomerase causes cell lysis
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