EC Number   |
Natural Substrates |
|---|
    3.6.1.5 | ATP + 2 H2O |
inhibition of platelet aggregation in the placenta |
| 3.6.1.5 | ATP + 2 H2O |
salvage of purine nucleobases in primary urine |
| 3.6.1.5 | ATP + 2 H2O |
regulation of extracellular ATP-level |
| 3.6.1.5 | ATP + 2 H2O |
inhibition of platelet aggregation |
| 3.6.1.5 | ATP + 2 H2O |
overall reaction |
| 3.6.1.5 | ATP + 2 H2O |
dissipation of ATP by CD39 reduces P2X7 receptor stimulation and thereby suppresses baseline leukocyte alphaMbeta2-integrin expression. As alphaMbeta2-integrin blockade reverses the postischemic, inflammatory phenotype of Cd39-/- mice. Phosphohydrolytic activity on the leukocyte surface suppresses cell-cell interactions that would otherwise promote thrombosis or inflammation |
| 3.6.1.5 | ATP + 2 H2O |
best substrate in hepatic stellate cells |
| 3.6.1.5 | ATP + 2 H2O |
CG5276 functions as apyrase converting extracellular ATP to ADP and AMP |
| 3.6.1.5 | ATP + 2 H2O |
ATP is hydrolyzed by NTPDase1 via ADP to AMP, without significant release of ADP |
| 3.6.1.5 | ATP + H2O |
- |
