EC Number   |
Natural Substrates  |
|---|
    3.5.1.2 | L-glutamine + H2O |
the enzyme plays a key role in energy and nitrogen metabolism, glutamate is a major excitatory neurotransmitter in neurons, especially in the cerebral cortex |
| 3.5.1.2 | L-glutamine + H2O |
PDX2 is a glutaminase that is involved in vitamin B6 biosynthesis |
| 3.5.1.2 | more |
the brain-specific BNIP-2-homology protein, BHIP-H is involved in enzyme regulation in neurons, loss of BNIP-H function could render glutamate excitotoxicity or/and deregulated glutamatergic activation, leading to ataxia, dystonia or other neurological disorders |
| 3.5.1.2 | more |
the spatial segregation of tissue-specific isozymes in pancreas alpha- and beta-cells may have important functional implications, facilitating a differential regulation of glutamate production in insulin- and glucagon-secreting cells, overview |
| 3.5.1.2 | more |
glutaminase as a potential component of the pathogenic process of human immunodeficiency virus associated dementia |
| 3.5.1.2 | more |
the enzyme prefers free L-glutamine to free L-asparagine, C-terminal glutaminyl, and asparaginyl residues in peptides |
