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Results 91 - 94 of 94

EC Number	Natural Substrates	Commentary (Nat. Sub.)
3.4.22.56	SETbeta + H2O	-
3.4.22.56	tau protein + H2O	cleavage by caspase-3 is a crucial upstream event associated with Tau self-assembly leading to Alzheimer's Disease pathogenesis
3.4.22.56	topoisomerase I + H2O	cleavage at DDVD146-/-Y and EEED170-/-G
3.4.22.56	transcription factor Pax7 + H2O	compensatory growth and regeneration of skeletal muscle is dependent on the resident stem cell population, satellite cells (SCs). Self-renewal and maintenance of the SC niche is coordinated by the paired-box transcription factor Pax7. Continued expression of this protein inhibits the myoblast differentiation program. Caspase 3 cleavage inactivation of Pax7 is a crucial step for terminating the self-renewal process

Results 91 - 94 of 94

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Release 2023.1 (January 2023)