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Results 41 - 46 of 46

EC Number	Natural Substrates	Commentary (Nat. Sub.)
3.4.22.49	Scc1 + H2O	Scc1 contains 2 separase cleavage sites
3.4.22.49	Scc1 + H2O	cleavage at 2 defined sites results in rapid destabilization of Scc1 and its dissociation from chromosomes
3.4.22.49	Slk19 + H2O	-
3.4.22.49	Slk19 + H2O	separase cleaves the kinetochore-associated protein Slk19 in metaphase-to-anaphase transition
3.4.22.49	Slk19 + H2O	a protein implicated in the mitotic exit via its role in the stabilization of spindle in budding yeast
3.4.22.49	SYN1 + H2O	the enzyme plays an essential role in embryo development. The enzyme is required for the removal of cohesin from meiotic chromosomes. The cleavage of SYN1 by separase is responsible for the release of sister chromatid cohesion during meiosis

Results 41 - 46 of 46

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Release 2023.1 (January 2023)