EC Number   |
Natural Substrates |
|---|
   3.2.2.23 | DNA + H2O |
involved in the repair of oxidized purines generated in the genome by endogenous or exogenous oxidative stress |
| 3.2.2.23 | DNA + H2O |
involved in replication-associated repair of oxidized bases |
| 3.2.2.23 | DNA + H2O |
important role in protecting DNA against oxidative free radicals and reactive oxygen-derived species |
| 3.2.2.23 | DNA + H2O |
biological substrates are purine oxidation products |
| 3.2.2.23 | DNA + H2O |
DNA base excision repair enzyme |
| 3.2.2.23 | DNA + H2O |
bifunctional base excision repair enzyme: DNA glycosylase/AP lyase |
| 3.2.2.23 | DNA containing 2,6-diamino-4-hydroxyformamidopyrimidine residues + H2O |
repair of the major DNA lesions 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxyformamidopyrimidine formed by reactive oxidative species |
| 3.2.2.23 | DNA containing 7-hydro-8-oxoguanine + H2O |
repairs oxidative DNA damage by efficiently removing formamidopyrimidine lesions and 8-oxoguanine residues from DNA |
| 3.2.2.23 | DNA containing 7-hydro-8-oxoguanine + H2O |
dublex, primary physiological substrate, DNA repair |
| 3.2.2.23 | DNA containing 8-hydroxyguanine residues + H2O |
natural substrate: 7,8-dihydro-8-oxo-dG, DNA base excision repair |
