EC Number |
Natural Substrates |
---|
3.1.4.4 | phosphatidylcholine + H2O |
hydrolysis of phosphatidylcholine by phospholipase D leads to the generation of phosphatidic acid, which is itself a source of diacylglycerol. PLD2 emerges as an early player upstream of the Ras-MAPK-IL-2 pathway in T-cells via phosphatidic acid and diacylglycerol production |
3.1.4.4 | phosphatidylcholine + H2O |
phosphatidic acid activates the production of and promotes accumulation of silymarin, overview |
3.1.4.4 | phosphatidylethanolamine + H2O |
parathyroid hormone stimulates phosphatidylethanolamine hydrolysis by phospholipase D in osteoblastic cells. Both phosphatidylcholine and phosphatidylethanolamine are substrates for phospholipase D in UMR-106 osteoblastic cells and can therefore be sources of phospholipid hydrolysis products for downstream signaling in osteoblast |
3.1.4.4 | phosphatidylethanolamine + H2O |
- |
3.1.4.4 | phosphatidylglycerol + H2O |
- |
3.1.4.4 | phosphatidylserine + H2O |
- |
3.1.4.4 | phospholipid + alcohol |
transphosphaditylation |
3.1.4.4 | phospholipid + H2O |
phosphoric ester hydrolysis |