EC Number   |
Natural Substrates |
|---|
    3.1.1.5 | more |
phospholipase B is necessary for the initiation of pulmonary infection by Cryptpococcus neoformans and for dissemination from the lung via the lymphatics. PLB1 plays a role in the binding of Cryptpococcus neoformans to host lung epithelial cells, possibly due to production of fatty acids from plasma memrane and/or surfactant by PLB activity |
| 3.1.1.5 | more |
phospholipase B1 is implicated in transcellular metabolism of macrophage-derived lipids. During both logarithmic and stationary phases of growth, the physiologically relevant phospholipids, dipalmitoyl phosphatidylcholine (DPPC) and dioleoyl phosphatidylcholine, are taken up and metabolized via PLB1 |
| 3.1.1.5 | more |
hydrolyzes sn-1 esters in lysophosphatidylcholine and lysophosphatidic acid |
| 3.1.1.5 | more |
acyl-CoA-binding protein 2 can bind both lysophosphatidylcholine and lysophospholipase 2 to promote the degradation of lysophosphatidylcholine in response to Cd2+-induced oxidative stress |
| 3.1.1.5 | phosphatidylcholine + H2O |
- |
