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<< < Results 11 - 20 of 33 > >>
EC Number Natural Substrates Commentary (Nat. Sub.)
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.135more LRAT plays an essential role in the regeneration of visual chromophore as well as in the metabolism of vitamin A, and is responsible for amidation of retinylamine, a potent and selective inhibitor of the retinoid cycle and 11-cis-retinal biosynthesis
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.135more LRAT plays an essential role in the regeneration of visual chromophore as well as in the metabolism of vitaminA, and is responsible for amidation of retinylamine, a potent and selective inhibitor of the retinoid cycle and 11-cis-retinal biosynthesis
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.135more retinoids, vitamin A, i.e.retinol, and related metabolites, have been shown to be important in regulating cell growth and differentiation, retinoid signaling, overview, expression of LRAT, which converts retinol to retinyl esters, is reduced in several human carcinomas as compared with adjacent normal tissue from the same organs, LRAT protein progressively decreases with a reduction in the degree of tumor differentiation in invasive breast carcinomas, overview
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.135more LRAT plays a role in maintaining a stable serum retinol concentration when dietary retinol concentration fluctuates
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.135palmitoyl-CoA + 11-cis-retinol-[cellular retinol-binding protein] esterification of 11-cis-retinol is four times greater than esterification of all-trans-retinol in Muller cells
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.135palmitoyl-CoA + all-trans-retinol-[cellular retinol-binding protein] esterification of 11-cis-retinol is four times greater than esterification of all-trans-retinol in Muller cells
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.135phosphatidylcholine + 11-cis-retinol essential for generation of the precursor for 11-cis-retinal, the visual chromophore in the eye
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.135phosphatidylcholine + 11-cis-retinol-[cellular-retinol-binding-protein] trans-esterification reaction is reversible, however in the presence of the isomerase, all-trans-retinyl esters are converted to 11-cis-retinol which is enzymatically oxidized to 11-cis-retinal, the chromophore of vision. Both all-trans-retinol and 11-cis-retinol are substrates for LRAT esterification, although all-transretinol is the preferred substrate.
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.135phosphatidylcholine + 11-cis-retinoll-[cellular-retinol-binding-protein] trans-esterification reaction is reversible, however in the presence of the isomerase, all-trans-retinyl esters are converted to 11-cis-retinol which is enzymatically oxidized to 11-cis-retinal, the chromophore of vision. Both all-trans-retinol and 11-cis-retinol are substrates for LRAT esterification, although all-transretinol is the preferred substrate.
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.135phosphatidylcholine + all-trans-retinol -
<< < Results 11 - 20 of 33 > >>