EC Number   |
Natural Substrates |
|---|
   3.6.5.4 | GDP + H2O |
- |
| 3.6.5.4 | GTP + H2O |
- |
| 3.6.5.4 | GTP + H2O |
cotranslational protein targeting to the plasma membrane, the Ffh-4.5S RNA ribonucleoprotein complex and the FtsY protein, respectively, form a unique complex in which both Ffh and FtsY act as GTPase activating proteins for one another, resulting in a mutual stimulation of GTP hydrolysis by both proteins, 4.5S RNA modulates the conformation of the Ffh-FtsY complex and may regulate its GTPase activity during the SRP functional cycle |
| 3.6.5.4 | GTP + H2O |
Ffh mediates SRP-dependent, cotranslational protein targeting to the plasma membrane, Ffh and FtsY, the latter being the GTPase subunit of the bacterial SRP receptor, act as GTPase activating proteins for one another, resulting in reciprocal stimulation of GTP hydrolysis |
| 3.6.5.4 | more |
FlhF is dispensable for protein targeting and for growth and viability, it plays a minor role in cell motility, the flhF gene is located within the che/fla operon |
| 3.6.5.4 | more |
light-harvesting chlorophyll a/b binding proteins are posttranslationally targeted to the thylakoid membrane by cpSRP, a heterodimer formed by cpSRP54 and cpSRP43 |
| 3.6.5.4 | GTP + H2O |
protein targeting by the SRP pathway, Ffh and FtsY, the GTPase subunit of the SRP receptor, reciprocally regulate each others GTPase activity, they interact only in a primed conformation which requires interdomain communication |
| 3.6.5.4 | GTP + H2O |
protein targeting to the plasma membrane |
| 3.6.5.4 | GTP + H2O |
protein targeting to the plasma membrane, signal recognition particle cycle, SRP and its receptor stimulate each others GTPase activity, GTP hydrolysis ensures unidirectional targeting of cargo through a translocation pore in the membrane |
| 3.6.5.4 | more |
Rpl25p plays a critical role in the recruitment of signal recognition particle to the ribosome |
