EC Number |
Metals/Ions |
Reference |
---|
7.2.2.19 | Cs+ |
activates |
711012 |
7.2.2.19 | Cs+ |
activates, Km: 1.25 mM, monovalent cations stimulate in the order of decreasing efficacy: Tl+, K+, Rb+, NH4+, Cs+ |
246851 |
7.2.2.19 | H+ |
activates |
733915 |
7.2.2.19 | H3O+ |
binds to the E1 conformation of the alpha-subunit of gastric proton pump, interaction similar to K+ interaction |
671711 |
7.2.2.19 | K+ |
- |
671711 |
7.2.2.19 | K+ |
activates |
687724, 733915 |
7.2.2.19 | K+ |
activates, activation by K+ is independent of the accompanying anion, obtaining maximal activity at about 0.5 mM and pH 7.4, Km is 1.9 mM, not effective at pH 6.6 |
711012 |
7.2.2.19 | K+ |
activates, required for ATPase activity |
685080 |
7.2.2.19 | K+ |
activates, required. But in the presence of 200m M KCl, ion binding sites are more than 99% saturated with K+. The enzyme activity under this condition is near zero |
711245 |
7.2.2.19 | K+ |
activates, with 0.11 mM as half saturating K+ concentration for both luminal binding sites, above 10 mM reduction of enzyme activity |
672636 |