EC Number   |
Metals/Ions |
Reference  |
|---|
    6.4.1.2 | phosphate |
phosphate content of the 10000000 MW enzyme form: 4.0 mol of phosphate per mol of subunit. Phosphate content of the 2000000 MW enzyme form: 6.0 mol phosphate per mol of subunit. The 10000000 MW subunit and the 2000000 MW subunit are interconvertible by phosphorylation and dephosphorylation. Dephosphorylation by [acetyl-CoA carboxylase]-phosphatase 2 activates the enzyme and reduces its dependence on citrate |
37571 |
| 6.4.1.2 | Mg2+ |
essential activator |
37574 |
| 6.4.1.2 | Mg2+ |
optimal concentration of 9686 enzyme: 5 mM, optimal concentration of Wayne enzyme: 3 mM |
37574 |
| 6.4.1.2 | Mn2+ |
no effect |
37574 |
| 6.4.1.2 | Cs+ |
greater activation at 1 mM HCO3- than at 10 mM HCO3- |
37576 |
| 6.4.1.2 | K+ |
greatest activation at 12-15 mM K+, at HCO3- concentration of 0.18 mM, 1 mM, and 10 mM |
37576 |
| 6.4.1.2 | Mg2+ |
free Mg2+ activates |
37576 |
| 6.4.1.2 | Mg2+ |
maximal activity at 3 mM Mg2+ with 1 mM ATP and at 4 mM Mg2+ with 3 mM ATP |
37576 |
| 6.4.1.2 | Mn2+ |
maximal activity at 1 mM Mn2+ with 1 mM ATP. Maximal activity is 25% of that observed with Mg2+ |
37576 |
| 6.4.1.2 | NH4+ |
greater activation at 1 mM HCO3- than at 10 mM HCO3- |
37576 |
