EC Number   |
Metals/Ions |
Reference |
|---|
    5.1.3.1 | Co2+ |
Co2+ is able to activate the enzyme in vitro |
716784 |
| 5.1.3.1 | Fe2+ |
RPE uses Fe2+ for catalysis |
714945 |
| 5.1.3.1 | Fe2+ |
the enzyme employs a ferrous iron atom as a solvent-exposed cofactor |
716784 |
| 5.1.3.1 | Mg2+ |
assay carried out at 10 mM Mg2+ |
672127 |
| 5.1.3.1 | Mn2+ |
manganese can activate the enzyme in vitro in place of iron converting the enzyme to a form that is unaffected by H2O2 |
716784 |
| 5.1.3.1 | more |
Ca2+, Cd2+, Cu2+, Mg2+, and Ni2+ do not activate the enzyme |
716784 |
| 5.1.3.1 | more |
no requirement for a divalent metal ion in catalysis |
653499 |
| 5.1.3.1 | Zn2+ |
Zn2+ is able to activate the enzyme in vitro |
716784 |
