EC Number |
Metals/Ions |
Reference |
---|
4.6.1.2 | Ca2+ |
- |
677989, 680671, 691110 |
4.6.1.2 | Ca2+ |
activates, is required for activation of the retinal enzyme by cone-specific calcium sensor guanylate cyclase activating protein 4 |
693267 |
4.6.1.2 | Ca2+ |
activation at 0.05 mM |
34843 |
4.6.1.2 | Ca2+ |
activation of soluble enzyme |
34843, 34850, 34851, 34867 |
4.6.1.2 | Ca2+ |
Ca2+-dependent negative feedback control mediated by guanylate-activating proteins |
651158 |
4.6.1.2 | Ca2+ |
dose-dependent stimulation |
680181 |
4.6.1.2 | Ca2+ |
modulates the membrane guanylate cyclase transduction machinery by both inhibiting and stimulating it involving the guanylate cyclae, the guanylate cyclase activating protein type 1, S100B, and neurocalcin delta, mechanism, overview |
692407 |
4.6.1.2 | Ca2+ |
the two neuronal calcium sensors, GCAP1 and GCAP2, confer Ca2+ sensitivity to guanylyl cyclase activity |
693152 |
4.6.1.2 | CO |
carbon monoxide is a modulator of neurotransmission in cardiac ganglia and in neural control of the adult human heart |
690679 |
4.6.1.2 | CO |
competitive binding, off rates are reduced by YC-1, but YC-1 stimulation of CO binding is unaltered for the heme-intact portion of both mutated proteins, CO release from msGC-NT1-CO is measured in a stopped-flow device by replacement with NO, which binds more quickly and tightly to the enzyme, overview |
693096 |