EC Number |
Metals/Ions |
Reference |
---|
4.2.1.12 | Fe2+ |
completely inactive in absence of divalent metal ion, Fe2+ is most effective |
33655 |
4.2.1.12 | Iron |
active site includes an Fe4S4 cluster |
33652 |
4.2.1.12 | Iron |
contains 4 Fe per 63000 Da subunit |
33652 |
4.2.1.12 | Iron |
enzyme contains 3.0 iron atoms per 63000 Da subunit |
33650 |
4.2.1.12 | Iron |
enzyme contains iron-sulfur clusters |
33658 |
4.2.1.12 | Iron |
Fe-S protein. 6-Phosphogluconate dehydratase activity is reduced during iron starvation in suf mutant. The de novo synthesis of the 4Fe-4S cluster in phosphogluconate dehydratase is impaired in the sufABCDSE mutant strain under iron starvation conditions |
666388 |
4.2.1.12 | Mg2+ |
completely inactive in absence of divalent metal ion, 45% of the activation by Fe2+ |
33655 |
4.2.1.12 | Mn2+ |
completely inactive in absence of divalent metal ion, 70% of the activation by Fe2+ |
33655 |
4.2.1.12 | Mn2+ |
the enzyme contains one Mn2+ per subunit, which is essential for activity, may be involved in binding of the substrate |
33652 |