EC Number   |
Metals/Ions |
Reference |
|---|
    4.1.3.17 | Cd2+ |
absolute requirement for divalent metal ion: Mg2+, Mn2+, Co2+, Zn2+ or Cd2+ |
33193 |
| 4.1.3.17 | Cd2+ |
Km: 0.0034 mM, reaction with L-4-carboxy-4-hydroxy-2-oxoadipate |
33193 |
| 4.1.3.17 | Co2+ |
absolute requirement for divalent metal ion: Mg2+, Mn2+, Co2+, Zn2+ or Cd2+ |
33193 |
| 4.1.3.17 | Co2+ |
activates |
33191 |
| 4.1.3.17 | Co2+ |
can replace Mg2+ |
650628 |
| 4.1.3.17 | Co2+ |
Km: 0.0077 mM, reaction with L-4-carboxy-4-hydroxy-2-oxoadipate |
33193 |
| 4.1.3.17 | Co2+ |
required, best activating metal ion, Km is 0.00838 mM for the wild-type enzyme, and 0.446 mM for the mutant E199A |
727049 |
| 4.1.3.17 | Co2+ |
required, equally activating as Ni2+ |
727049 |
| 4.1.3.17 | Mg2+ |
a magnesium ion is coordinated directly or indirectly via water through interactions with Asp102, Asp124, and Glu199 |
727049 |
| 4.1.3.17 | Mg2+ |
absolute requirement for divalent metal ion: Mg2+, Mn2+, Co2+, Zn2+ or Cd2+ |
33193 |
