EC Number   |
Metals/Ions |
Reference |
|---|
   3.5.3.15 | Ba2+ |
Ba2+ activates isozymes PAD 1 and 3 to about 15% and 2.5%, respectively, of the level of Ca2+ |
711246 |
| 3.5.3.15 | Ca2+ |
- |
209432, 685064, 685554 |
| 3.5.3.15 | Ca2+ |
1 mM required for maximal deimination of filaggrin, peptidylarginine deiminase 1. Maximal deamination of benzoyl-L-Arg ethyl ester at 4 mM or above |
664565 |
| 3.5.3.15 | Ca2+ |
1.5 mM required for maximal deimination of filaggrin, peptidylarginine deiminase 3, maximal deimination of benzoyl-L-Arg ethyl ester at 4 mM or above |
664565 |
| 3.5.3.15 | Ca2+ |
10 mM, 11% of the activity with Ca2+ |
209412 |
| 3.5.3.15 | Ca2+ |
2.5 mM required for maximal deamination of filaggrin, peptidylarginine deiminase 2. Maximal deimination of benzoyl-L-Arg ethyl ester at 4 mM or above |
664565 |
| 3.5.3.15 | Ca2+ |
absolutely required, K0.5 value 0.18 mM. The enzyme binds calcium in a stepwise fashion |
752353 |
| 3.5.3.15 | Ca2+ |
Ca2+ is not only the indispensable factor in the environment of deimination reaction, but is also considered as a major regulator of PAD genes at the transcriptional level |
699211 |
| 3.5.3.15 | Ca2+ |
dependent on |
686015, 686294, 710772, 712024, 733680 |
| 3.5.3.15 | Ca2+ |
dependent on, binding structure, overview |
666755 |
