EC Number |
Metals/Ions |
Reference |
---|
3.4.24.63 | Ca2+ |
physiologic calcium concentrations display a dual role by (1) directly inhibiting meprin beta activity and (2) supporting meprin beta folding during biosynthesis |
733822 |
3.4.24.63 | Ca2+ |
required |
752474 |
3.4.24.63 | more |
metalloendopeptidase according to inhibition profile |
31024, 31031 |
3.4.24.63 | Zn2+ |
a metalloprotease |
733288, 734610 |
3.4.24.63 | Zn2+ |
a single-zinc metalloendoprotease |
755294 |
3.4.24.63 | Zn2+ |
a zinc metalloprotease |
752709 |
3.4.24.63 | Zn2+ |
a zinc metalloprotease with the zinc-binding motif HExxHxxGxxHE(or M) |
683206 |
3.4.24.63 | Zn2+ |
a zinc metalloproteinase |
733519, 752990, 754236, 754397 |
3.4.24.63 | Zn2+ |
a zinc-dependent metalloprotease |
753172, 753218, 753321, 753536, 753697, 753929, 754028, 754779, 755466 |
3.4.24.63 | Zn2+ |
meprin beta is a metalloprotease of the astacin family characterized by a conserved zinc-binding motif (HExxHxxGFxHExxRxDR) |
734332 |