EC Number   |
Metals/Ions |
Reference |
|---|
   3.4.24.44 | Ca2+ |
low concentrations stabilize proteolytic activity |
668847 |
| 3.4.24.44 | Co2+ |
can be directly exchanged for zinc by dialysis without loss of specificity or activity |
31259, 31276 |
| 3.4.24.44 | Co2+ |
no conformational change accompanies the metal exchange |
31276 |
| 3.4.24.44 | more |
metal analysis detects 0.42 mol Ca2+ and 0.05 mol Mg2+ per mol enzyme |
31261 |
| 3.4.24.44 | Zn2+ |
1 mol zinc/mol enzyme |
31259, 31260, 31261 |
| 3.4.24.44 | Zn2+ |
can be replaced by Co2+, which does not significantly alter the proteolytic activity |
668847 |
| 3.4.24.44 | Zn2+ |
zinc metalloproteinase |
31259, 31260, 31261, 31276 |
| 3.4.24.44 | Zn2+ |
zinc removal causes large structural perturbations replacing it with Co2+ is accomplished without structural changes |
31276 |
