EC Number   |
Metals/Ions |
Reference |
|---|
   3.4.21.22 | Ca2+ |
- |
649933, 650104, 652413, 652507, 669860, 691159, 95339 |
| 3.4.21.22 | Ca2+ |
4-8fold allosteric activation at 5 mM |
650224 |
| 3.4.21.22 | Ca2+ |
5 mM used in assay conditions |
752991 |
| 3.4.21.22 | Ca2+ |
5 mM, optimal concentration for cleavage of factor X by factor IXa on phospholipid membranes |
649923 |
| 3.4.21.22 | Ca2+ |
activates |
683165, 684024, 684077 |
| 3.4.21.22 | Ca2+ |
binding of a subpopulation of platelets to the enzyme is activated by the protease-activated receptor-1, PAR-1, requirring both release of calcium from internal stores and influx of extracellular calcium, overview |
683154 |
| 3.4.21.22 | Ca2+ |
Ca2+ enhances the activity of factor IXa (5 mM used in assay conditions) |
732403 |
| 3.4.21.22 | Ca2+ |
factor IX activation is the first calcium-dependent reaction in intrinsic system clotting |
95337 |
| 3.4.21.22 | Ca2+ |
factor IXa contains a high-affinity Ca2+-binding site |
718322 |
| 3.4.21.22 | Ca2+ |
for proper binding of factor IXa to phospholipid and factor VIIIa, all of the Ca2+-sites in factor IXa must be filled |
652114 |
